李俊杰,男,教授,博士,博士生导师,9001cc金沙以诚为本副院长,兼任中国畜牧兽医学会动物繁殖学分会副理事长、河北农业大学学术委员会委员、中国动物学会生殖生物学分会委员、中国农机学会养猪学分会理事。
2008-2011年在中国农业大学动物遗传育种与繁殖专业攻读博士学位。2015-2016年获教育部留学基金委资助赴日本东京大学进行访问学者研究。主要从事哺乳动物配子/胚胎生物技术、动物繁殖调控等工作,主持国家自然科学基金面上项目、“十四五”国家重点研发计划课题、科技部农业科技成果转化资金项目、河北省自然科学基金、河北省重点研发计划等科研课题20余项;获科技奖励7项,其中获河北省科技进步二等奖6项。指导的研究生毕业论文3次荣获河北省优秀硕士学位论文。在《Theriogenology》、《International Journal of Molecular Sciences》、《Animal Reproduction Science》、《中国农业科学》、《畜牧兽医学报》等刊物发表论文150余篇;副主编《动物配子与胚胎冷冻保存原理及应用》、《牛羊繁殖十大控制技术》、《实用畜禽繁殖学》、《母猪批次化生产管理技术》等著作19部。
所授课程:
动物繁殖学,动物生物化学
主要研究方向和科研项目:
1、 研究方向:动物胚胎工程,动物繁殖调控
2、近年来承担的科研项目:
(1)“十四五”国家重点研发计划课题——母猪批次化生产妊娠调控技术研究(2022YFD1300303),240万元,起止年限:2022.12-2027.11,第一;
(2)国家自然科学基金——Sirt2通过线粒体自噬调控绵羊卵母细胞体外成熟机制研究(32272871),54万元,起止年限:2023.01-2026.12,第一;
(3)“十四五”国家重点研发计划——北方珍稀濒危牛羊种质资源抢救性保护研究(2021YFD1200401)子课题,393万元,起止年限:2021.12-2026.11,第一;
(4)河北省现代农业产业技术体系创新团队生猪高效繁殖岗位(HBCT2023170202),135万元,起止年限:2023 -2027,第一;
(5)“母猪定时输精与批次化生产关键技术研究与示范(20326615D)”,河北省重点研发计划,30万元,起止年限:2020.6-2023.6,第一;
(6)“Sirt2 对绵羊卵母细胞线粒体功能的影响研究(ZD2020108)”,河北省教育厅重点项目,第一,8万元,起止年限:2020.1-2023.12;
获得的科技奖项:
1、“应用生物技术加快纯(良)种肉羊繁殖效率研究与开发”,河北省科技进步二等奖,第3名;
2、“优质、高产奶牛快速繁殖技术研究与产业化示范”,河北省科技进步二等奖,第4名;
3、“肉羊快速繁殖技术研究、集成与推广”,河北省科技进步二等奖,第3名;
4、“羊克隆、高效超排及精液冷冻研究与产业化示范”,河北省科技进步二等奖,第3名;
5、“华北农区高产奶牛良种繁育体系建立与示范”,河北省科技进步二等奖,第8名;
6、“幼羔超排缩短世代间隔的快速繁育关键技术”,河北省科技进步二等奖,第4名;
7、“肉羊卵母细胞冷冻、体细胞核移植与胚胎移植关键技术”,保定市科技进步一等奖,第1名。
代表性论文:
1、Fang, X.; Xia, W.; Li, S.; Qi, Y.; Liu, M.; Yu, Y.; Li, H.; Li, M.; Tao, C.; Wang, Z.; Li, J(correspondent author). SIRT2 Is Critical for Sheep Oocyte Maturation through Regulating Function of Surrounding Granulosa Cells. Int. J. Mol. Sci. 2022, 23(9), 5013. https://doi.org/10.3390/ijms23095013
2、Q. Zhao, C. Tao, J. Pan, Q. Wei , Z. Zhu , L. Wang , M. Liu , J. Huang , F. Yu , X. Chen , L. Zhang, J. Li(correspondent author).Equine chorionic gonadotropin pretreatment 15 days before fixed-time artificial insemination improves the reproductive performance of replacement gilts. Animal, 2021 (15): 100406.
3、Zhao Qianqian,, Xia Wei, Liu Chuang,, Cui Zhenliang , Wei Qiaoli ,Liu Mingzhi , Wang Longyan , Bai Rui , Tian Jianhui , Junjie Li(correspondent author),Weng Shiqiao. MicroRNAs are potential regulators of the timed artificial insemination effect in gilt endometrium. Animal Reproduction Science. 2021 (233): 106837.
4、Yi Fang, Wei Xia, Wentao Cai, Xiaosheng Zhang, Jinlong Zhang, Xiangwei Fu, Sa Li, Xiaohuan Fang, Shuchun Sun, Zhigang Wang, Xiaolei Zhang, Shien Zhu, Junjie Li(correspondent author). Effects of TLR4 overexpression on sperm quality, seminal plasma biomarkers, sperm DNA methylation and pregnancy rate in sheep[J]. Theriogenology, 2020, 15(142): 368-375.
5、Wei Xia, Qiaoli Wei, Mingzhi Liu, Chuang Liu, Qianqian Zhao, Xiaoyu Chen, Zhiwei Zhu, Xiaohuan Fang, Sa Li, Xiaolei Zhang, Weidong Hua, Jianzhi Pan, Jianhui Tian, Junjie Li(correspondent author). Effect of fixed-time artificial insemination on corpus luteum gene expression at the day 16 and 25 pregnancy of gilt. Anim Biotechnol. 2021 May 3:1-9. doi: 10.1080/10495398.2021.1914068. Epub ahead of print. PMID: 33941027.
6、Hui Cao, Jun Li, Wenlong Su, Junjie Li(correspondent author), Zhigang Wang, Shuchun Sun, Shujun Tian, Lu Li, Hanyang Wang, Jiexin Li. Zebularine significantly improves the preimplantation development of ovine somatic cell nuclear transfer embryos[J]. Reprod Fertil Dev, 2019, 31(2): 357-365.
7、Xiaohuan Fang, Wei Xia, Hui Cao, Yanhua Guo, Han Wang, Xiaosheng Zhang, Pengcheng Wan, Chuang Liu, Qiaoli Wei, Shuchun Sun, Shujun Tian, Junjie Li(correspondent author), Zhigang Wang. Effect of supplemetation of Zebularine and Scriptaid on efficiency of in vitro developmental competence of ovine somatic cell nuclear transferred embryos[J]. Animal Biotechnology, 2020, 31(2): 155-163.
8、Lu Li, Yuehui Ma, Xianglong Li, Xiangchen Li, Chunyu Bai, Meng Ji, Shuang Zhang, Weijun Guan, and Junjie Li(correspondent author). Isolation, Culture, and Characterization of Chicken Cartilage Stem/Progenitor Cells. BioMed Research International, 2015:586290.
9、 Bing-Qiang Wen, Jun Li, Jun-Jie Li(correspondent author), Shu-Jun Tian, Shu-Chun Sun, Xin Qi, Wen-Tao Cai, Qing-Ling Chang. The histone deacetylase inhibitor Scriptaid improves in vitrodevelopmental competence of ovine somatic cell nuclear transferred embryos[J]. Theriogenology 2014, (81) : 332–339.
10、X.H. Mo, X.W. Fu, D.S. Yuan, G.Q. Wu, B.Y. Jia, K.R. Cheng, M. Du, Y.H. Zhou, M.X. Yue, Y.P. Hou, Jun-Jie Li(correspondent author), S.E. Zhu. Effect of meiotic status, cumulus cells and cytoskeleton stabilizer on the developmental competence of ovine oocytes following vitrification. Small Ruminant Research, 2014 (117):151–157.
11、J.J.Li, X.W.Fu, X.H.Mo, M.X.Yue, B.Y.Jia, S.E.Zhu. Vitrification alters acH4K12 and acH4K16 levels in sheep oocytes at various developmental stages. Small Ruminant Research, 2013 (112): 108-113
12、Jun-Jie Li, Yan Pei , Guang-Bin Zhou, Lun Suo, Yan-Ping Wang, Guo-Quan Wu, Xiang-Wei Fu, Yun-Peng Hou and Shi-En Zhu. HISTONE DEACETYLTRANSFERASE1 EXPRESSION IN MOUSE OOCYTE AND THEIR IN VITRO-FERTILIZED EMBRYO: EFFECT OF OOCYTE VITRIFICATION[J]. CryoLetters, 2011,32 (1), 13-20.
13、房晓欢,李俊杰(通讯作者). 线粒体自噬调节雌性动物生殖功能的研究进展[J]. 畜牧兽医学报,2021,52(1):1-8.
14、李俊杰,李俊,孙洁,桑润滋.提高山羊卵丘细胞核移植效果的研究[J].中国农业科学,2009,42(6):2142-2148.
15、李俊杰,桑润滋,田树军,倪俊卿,杨庆华,张军辉,胡月超,马亚宾,吴云海. 不同季节肉用种公牛精液品质与生理常值、血清及精清生化指标相关关系研究[J]. 畜牧兽医学报,2006,37(3):232-241.
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